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flc lambda elisa kit  (Sebia Inc)

 
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    Sebia Inc flc lambda elisa kit
    A Effect of mycolactone on MM.1S, JIM3, and KMS‐11 cell viability after 48 and 72 h of treatment, as measured by exposure of Annexin V and incorporation of PI. Data are Mean % of live, apoptotic, and dead cells from technical duplicates, gated as in Appendix Fig , relative to total cells. B, C Inhibitory effect of mycolactone on cell expression of CD38 (Type II) and CD138, IL‐6R, and CD40 (Type I) transmembrane proteins (B). Stimulatory effect of mycolactone on cell expression of BCMA, a Type III transmembrane protein (C). Mean fluorescence intensities (MFIs) were measured in live cells 48 h after addition of mycolactone. Data are Mean MFIs ± SD from technical duplicates of two independent experiments, relative to vehicle‐treated controls (Ctrl). D Inhibitory effect of mycolactone on immunoglobulin <t>(lambda</t> chain) secretion, as quantified by <t>ELISA</t> in culture supernatants after 24 h of treatment. Data are Mean concentrations ± SD of secreted lambda chain (µg/ml) from technical duplicates of two independent experiments (MM.1S) or Mean of secreted lambda chain concentrations (µg/ml) from technical duplicates (JIM3 and KMS‐11), relative to vehicle‐treated controls. E Correlation between immunoglobulin lambda chain (Ig) secretion after 24 h (D) and MM cell line mortality after 72 h (A), in the three cell lines treated with 50 nM mycolactone. Slopes (R) and statistical significance ( P values) are indicated. Data information: In A (all cell lines) and D (JIM3 and KMS‐11), shown data are representative of two independent experiments with similar results.
    Flc Lambda Elisa Kit, supplied by Sebia Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/flc lambda elisa kit/product/Sebia Inc
    Average 90 stars, based on 1 article reviews
    flc lambda elisa kit - by Bioz Stars, 2026-03
    90/100 stars

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    1) Product Images from "The Sec61 translocon is a therapeutic vulnerability in multiple myeloma"

    Article Title: The Sec61 translocon is a therapeutic vulnerability in multiple myeloma

    Journal: EMBO Molecular Medicine

    doi: 10.15252/emmm.202114740

    A Effect of mycolactone on MM.1S, JIM3, and KMS‐11 cell viability after 48 and 72 h of treatment, as measured by exposure of Annexin V and incorporation of PI. Data are Mean % of live, apoptotic, and dead cells from technical duplicates, gated as in Appendix Fig , relative to total cells. B, C Inhibitory effect of mycolactone on cell expression of CD38 (Type II) and CD138, IL‐6R, and CD40 (Type I) transmembrane proteins (B). Stimulatory effect of mycolactone on cell expression of BCMA, a Type III transmembrane protein (C). Mean fluorescence intensities (MFIs) were measured in live cells 48 h after addition of mycolactone. Data are Mean MFIs ± SD from technical duplicates of two independent experiments, relative to vehicle‐treated controls (Ctrl). D Inhibitory effect of mycolactone on immunoglobulin (lambda chain) secretion, as quantified by ELISA in culture supernatants after 24 h of treatment. Data are Mean concentrations ± SD of secreted lambda chain (µg/ml) from technical duplicates of two independent experiments (MM.1S) or Mean of secreted lambda chain concentrations (µg/ml) from technical duplicates (JIM3 and KMS‐11), relative to vehicle‐treated controls. E Correlation between immunoglobulin lambda chain (Ig) secretion after 24 h (D) and MM cell line mortality after 72 h (A), in the three cell lines treated with 50 nM mycolactone. Slopes (R) and statistical significance ( P values) are indicated. Data information: In A (all cell lines) and D (JIM3 and KMS‐11), shown data are representative of two independent experiments with similar results.
    Figure Legend Snippet: A Effect of mycolactone on MM.1S, JIM3, and KMS‐11 cell viability after 48 and 72 h of treatment, as measured by exposure of Annexin V and incorporation of PI. Data are Mean % of live, apoptotic, and dead cells from technical duplicates, gated as in Appendix Fig , relative to total cells. B, C Inhibitory effect of mycolactone on cell expression of CD38 (Type II) and CD138, IL‐6R, and CD40 (Type I) transmembrane proteins (B). Stimulatory effect of mycolactone on cell expression of BCMA, a Type III transmembrane protein (C). Mean fluorescence intensities (MFIs) were measured in live cells 48 h after addition of mycolactone. Data are Mean MFIs ± SD from technical duplicates of two independent experiments, relative to vehicle‐treated controls (Ctrl). D Inhibitory effect of mycolactone on immunoglobulin (lambda chain) secretion, as quantified by ELISA in culture supernatants after 24 h of treatment. Data are Mean concentrations ± SD of secreted lambda chain (µg/ml) from technical duplicates of two independent experiments (MM.1S) or Mean of secreted lambda chain concentrations (µg/ml) from technical duplicates (JIM3 and KMS‐11), relative to vehicle‐treated controls. E Correlation between immunoglobulin lambda chain (Ig) secretion after 24 h (D) and MM cell line mortality after 72 h (A), in the three cell lines treated with 50 nM mycolactone. Slopes (R) and statistical significance ( P values) are indicated. Data information: In A (all cell lines) and D (JIM3 and KMS‐11), shown data are representative of two independent experiments with similar results.

    Techniques Used: Expressing, Fluorescence, Enzyme-linked Immunosorbent Assay



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    flc lambda elisa kit  (Sebia Inc)
    90
    Sebia Inc flc lambda elisa kit
    A Effect of mycolactone on MM.1S, JIM3, and KMS‐11 cell viability after 48 and 72 h of treatment, as measured by exposure of Annexin V and incorporation of PI. Data are Mean % of live, apoptotic, and dead cells from technical duplicates, gated as in Appendix Fig , relative to total cells. B, C Inhibitory effect of mycolactone on cell expression of CD38 (Type II) and CD138, IL‐6R, and CD40 (Type I) transmembrane proteins (B). Stimulatory effect of mycolactone on cell expression of BCMA, a Type III transmembrane protein (C). Mean fluorescence intensities (MFIs) were measured in live cells 48 h after addition of mycolactone. Data are Mean MFIs ± SD from technical duplicates of two independent experiments, relative to vehicle‐treated controls (Ctrl). D Inhibitory effect of mycolactone on immunoglobulin <t>(lambda</t> chain) secretion, as quantified by <t>ELISA</t> in culture supernatants after 24 h of treatment. Data are Mean concentrations ± SD of secreted lambda chain (µg/ml) from technical duplicates of two independent experiments (MM.1S) or Mean of secreted lambda chain concentrations (µg/ml) from technical duplicates (JIM3 and KMS‐11), relative to vehicle‐treated controls. E Correlation between immunoglobulin lambda chain (Ig) secretion after 24 h (D) and MM cell line mortality after 72 h (A), in the three cell lines treated with 50 nM mycolactone. Slopes (R) and statistical significance ( P values) are indicated. Data information: In A (all cell lines) and D (JIM3 and KMS‐11), shown data are representative of two independent experiments with similar results.
    Flc Lambda Elisa Kit, supplied by Sebia Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/flc lambda elisa kit/product/Sebia Inc
    Average 90 stars, based on 1 article reviews
    flc lambda elisa kit - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier

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    A Effect of mycolactone on MM.1S, JIM3, and KMS‐11 cell viability after 48 and 72 h of treatment, as measured by exposure of Annexin V and incorporation of PI. Data are Mean % of live, apoptotic, and dead cells from technical duplicates, gated as in Appendix Fig , relative to total cells. B, C Inhibitory effect of mycolactone on cell expression of CD38 (Type II) and CD138, IL‐6R, and CD40 (Type I) transmembrane proteins (B). Stimulatory effect of mycolactone on cell expression of BCMA, a Type III transmembrane protein (C). Mean fluorescence intensities (MFIs) were measured in live cells 48 h after addition of mycolactone. Data are Mean MFIs ± SD from technical duplicates of two independent experiments, relative to vehicle‐treated controls (Ctrl). D Inhibitory effect of mycolactone on immunoglobulin (lambda chain) secretion, as quantified by ELISA in culture supernatants after 24 h of treatment. Data are Mean concentrations ± SD of secreted lambda chain (µg/ml) from technical duplicates of two independent experiments (MM.1S) or Mean of secreted lambda chain concentrations (µg/ml) from technical duplicates (JIM3 and KMS‐11), relative to vehicle‐treated controls. E Correlation between immunoglobulin lambda chain (Ig) secretion after 24 h (D) and MM cell line mortality after 72 h (A), in the three cell lines treated with 50 nM mycolactone. Slopes (R) and statistical significance ( P values) are indicated. Data information: In A (all cell lines) and D (JIM3 and KMS‐11), shown data are representative of two independent experiments with similar results.

    Journal: EMBO Molecular Medicine

    Article Title: The Sec61 translocon is a therapeutic vulnerability in multiple myeloma

    doi: 10.15252/emmm.202114740

    Figure Lengend Snippet: A Effect of mycolactone on MM.1S, JIM3, and KMS‐11 cell viability after 48 and 72 h of treatment, as measured by exposure of Annexin V and incorporation of PI. Data are Mean % of live, apoptotic, and dead cells from technical duplicates, gated as in Appendix Fig , relative to total cells. B, C Inhibitory effect of mycolactone on cell expression of CD38 (Type II) and CD138, IL‐6R, and CD40 (Type I) transmembrane proteins (B). Stimulatory effect of mycolactone on cell expression of BCMA, a Type III transmembrane protein (C). Mean fluorescence intensities (MFIs) were measured in live cells 48 h after addition of mycolactone. Data are Mean MFIs ± SD from technical duplicates of two independent experiments, relative to vehicle‐treated controls (Ctrl). D Inhibitory effect of mycolactone on immunoglobulin (lambda chain) secretion, as quantified by ELISA in culture supernatants after 24 h of treatment. Data are Mean concentrations ± SD of secreted lambda chain (µg/ml) from technical duplicates of two independent experiments (MM.1S) or Mean of secreted lambda chain concentrations (µg/ml) from technical duplicates (JIM3 and KMS‐11), relative to vehicle‐treated controls. E Correlation between immunoglobulin lambda chain (Ig) secretion after 24 h (D) and MM cell line mortality after 72 h (A), in the three cell lines treated with 50 nM mycolactone. Slopes (R) and statistical significance ( P values) are indicated. Data information: In A (all cell lines) and D (JIM3 and KMS‐11), shown data are representative of two independent experiments with similar results.

    Article Snippet: Supernatants from MM cells cultures treated with mycolactone and/or BZ alone were collected after 24 h, and the concentration of free light chain was assessed using the SEBIA FLC lambda ELISA kit (SEBIA, 5101) according to the manufacturer’s recommendations.

    Techniques: Expressing, Fluorescence, Enzyme-linked Immunosorbent Assay